# OnCo record apoptosis (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/apoptosis/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "apoptosis" ;
  schema:name "Apoptosis"@en ;
  schema:alternateName "apoptotic"@en, "programmed cell death"@en, "cell death"@en, "pro-apoptotic"@en, "anti-apoptotic"@en, "undergo apoptosis"@en, "induce apoptosis"@en, "induces apoptosis"@en, "triggers apoptosis"@en ;
  schema:description "The cell's built-in self-destruct programme, which tidily dismantles a damaged or unwanted cell without alarming its neighbours. Cancer cells disable it by mutating TP53 or overproducing BCL-2; chemotherapy and radiation work largely by inflicting enough damage to trigger it, and venetoclax removes the BCL-2 shield directly."@en ;
  schema:url <https://onco.cc/terms/apoptosis/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Apoptosis> ;
  owl:sameAs <http://www.wikidata.org/entity/Q14599311> ;
  schema:citation <https://en.wikipedia.org/wiki/Apoptosis> ;
  onco:related <https://onco.cc/terms/necrosis/>, <https://onco.cc/terms/resisting-cell-death/>, <https://onco.cc/terms/immunogenic-cell-death/>, <https://onco.cc/terms/tumour-suppressor-gene/>, <https://onco.cc/pathways/ferroptosis-cell-death/> ;
  onco:targets <https://onco.cc/targets/bcl2/>, <https://onco.cc/targets/tp53/> ;
  onco:drugs <https://onco.cc/drugs/venetoclax/> ;
  onco:pathways <https://onco.cc/pathways/apoptosis-bcl2/>, <https://onco.cc/pathways/p53-cell-cycle/> .