# OnCo record appendiceal-adenocarcinoma (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/appendiceal-adenocarcinoma/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "appendiceal-adenocarcinoma" ;
  schema:name "Appendiceal adenocarcinoma (mucinous and non-mucinous, including signet ring cell)"@en ;
  schema:alternateName "Appendix adenocarcinoma"@en, "Colonic-type appendiceal adenocarcinoma"@en, "Mucinous appendiceal adenocarcinoma"@en, "Signet ring cell carcinoma of the appendix"@en, "High-grade appendiceal cancer"@en ;
  schema:description "Appendiceal adenocarcinoma is the invasive, gland-forming form of appendix cancer that behaves more like bowel cancer than the jelly-producing low-grade tumours, spreading to lymph nodes and the abdominal lining. It is treated with right hemicolectomy and bowel-cancer chemotherapy, and peritoneal spread with cytoreductive surgery and heated intraperitoneal chemotherapy in fit patients."@en ;
  schema:url <https://onco.cc/cancers/appendiceal-adenocarcinoma/> ;
  schema:dateModified "2026-09-18"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Appendix_cancer> ;
  schema:citation <https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1428>, <https://en.wikipedia.org/wiki/Appendix_cancer> ;
  onco:tag "subtype-page", "gastrointestinal" ;
  onco:related <https://onco.cc/cancers/low-grade-appendiceal-mucinous-neoplasm/>, <https://onco.cc/cancers/goblet-cell-adenocarcinoma/>, <https://onco.cc/cancers/appendiceal/>, <https://onco.cc/cancers/colorectal/> ;
  onco:technologies <https://onco.cc/technologies/hipec/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/ct/>, <https://onco.cc/technologies/mri/>, <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:targets <https://onco.cc/targets/kras/>, <https://onco.cc/targets/tp53/> ;
  onco:drugs <https://onco.cc/drugs/folfox/>, <https://onco.cc/drugs/capox/>, <https://onco.cc/drugs/folfiri/>, <https://onco.cc/drugs/bevacizumab/>, <https://onco.cc/drugs/mitomycin/>, <https://onco.cc/drugs/pembrolizumab/> ;
  onco:terms <https://onco.cc/terms/hipec-procedure/>, <https://onco.cc/terms/peritoneal-metastasis/>, <https://onco.cc/terms/colectomy/>, <https://onco.cc/terms/lymphadenectomy/>, <https://onco.cc/terms/msi/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-chicago-consensus-appendiceal-neoplasms-cancer-2020/>, <https://onco.cc/key-papers/paper-who-2019-digestive-system-tumours-nagtegaal-histopathology-2020/>, <https://onco.cc/key-papers/paper-psogi-pseudomyxoma-appendiceal-classification-am-j-surg-pathol-2016/> ;
  onco:pipeline <https://onco.cc/drugs/folfox/>, <https://onco.cc/technologies/hipec/>, <https://onco.cc/drugs/pembrolizumab/> ;
  onco:standardOfCare <https://onco.cc/terms/colectomy/>, <https://onco.cc/terms/lymphadenectomy/>, <https://onco.cc/drugs/folfox/>, <https://onco.cc/drugs/capox/>, <https://onco.cc/technologies/hipec/>, <https://onco.cc/terms/hipec-procedure/>, <https://onco.cc/drugs/mitomycin/>, <https://onco.cc/drugs/folfox/>, <https://onco.cc/drugs/capox/>, <https://onco.cc/terms/peritoneal-metastasis/>, <https://onco.cc/drugs/folfox/>, <https://onco.cc/drugs/capox/>, <https://onco.cc/drugs/bevacizumab/>, <https://onco.cc/drugs/folfiri/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/terms/msi/>, <https://onco.cc/drugs/folfox/>, <https://onco.cc/drugs/capox/>, <https://onco.cc/technologies/hipec/> .