# OnCo record aptn-101 (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/aptn-101/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "aptn-101" ;
  schema:name "APTN-101"@en ;
  schema:alternateName "hEGFRvIII-CD3 bi-scFv"@en, "EGFRvIII BRiTE"@en ;
  schema:description "APTN-101 is a two-armed antibody from Adaptin Bio that steers a patient's own T cells against brain tumour cells carrying a faulty growth receptor. It is in a first trial in people with glioblastoma at Duke University."@en ;
  schema:url <https://onco.cc/drugs/aptn-101/> ;
  schema:dateModified "2026-11-04"^^xsd:date ;
  schema:citation <https://www.sec.gov/Archives/edgar/data/1938571/000121390026095034/ea0303043-s1_adaptin.htm> ;
  onco:status "phase-1" ;
  onco:tag "pipeline" ;
  onco:modality "Bispecific T cell engager (EGFRvIII x CD3)" ;
  onco:technologies <https://onco.cc/technologies/t-cell-engager/> ;
  onco:targets <https://onco.cc/targets/cd3/> ;
  onco:companies <https://onco.cc/companies/adaptin-bio/> ;
  onco:terms <https://onco.cc/terms/egfrviii/> .