# OnCo record ar-v7-splice-variant (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/ar-v7-splice-variant/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "ar-v7-splice-variant" ;
  schema:name "AR-V7 splice variant"@en ;
  schema:alternateName "AR-V7"@en, "AR-V7 positive"@en, "androgen receptor splice variant 7"@en, "AR-V7 CTC"@en, "nuclear AR-V7"@en ;
  schema:description "AR-V7 is a shortened androgen receptor that lacks the part hormone drugs bind, so it stays active without testosterone. Found in circulating tumour cells, it predicts poor response to abiraterone and enzalutamide, but no label uses it yet."@en ;
  schema:url <https://onco.cc/biomarkers/ar-v7-splice-variant/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02269982> ;
  onco:tag "biomarker", "prostate", "no-approval" ;
  onco:related <https://onco.cc/biomarkers/psma-pet-expression/> ;
  onco:cancers <https://onco.cc/cancers/prostate-mcrpc/>, <https://onco.cc/cancers/prostate/> ;
  onco:drugs <https://onco.cc/drugs/abiraterone/>, <https://onco.cc/drugs/enzalutamide/> ;
  onco:terms <https://onco.cc/terms/ar-v7/> .