# OnCo record araf (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/araf/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "araf" ;
  schema:name "ARAF"@en ;
  schema:alternateName "A-Raf proto-oncogene, serine/threonine kinase"@en, "Serine/threonine-protein kinase A-Raf"@en, "A-Raf"@en, "ARAF1"@en, "ARAF" ;
  schema:description "ARAF (Serine/threonine-protein kinase A-Raf) is a protein kinase, an enzyme that switches other proteins on by adding phosphate groups. The public catalogues list it as a drug target, an oncogene driver and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Lung cancer, Colorectal cancer, Langerhans cell histiocytosis and 4 more."@en ;
  schema:url <https://onco.cc/targets/araf/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:646>, <https://www.uniprot.org/uniprotkb/P10398/entry>, <https://www.ncbi.nlm.nih.gov/gene/369>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000078061> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "kinase" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:646>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000078061>, <https://www.uniprot.org/uniprotkb/P10398/entry>, <https://www.ncbi.nlm.nih.gov/gene/369> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/langerhans-cell-histiocytosis/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/erdheim-chester-disease/>, <https://onco.cc/cancers/cholangiocarcinoma/>, <https://onco.cc/cancers/sclc/> .