# OnCo record arches (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/arches/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "arches", "NCT02677896" ;
  schema:name "ARCHES"@en ;
  schema:description "Brought enzalutamide into first-line metastatic treatment, with an overall survival benefit confirmed in 2021."@en ;
  schema:url <https://onco.cc/trials/arches/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02677896>, <https://www.nice.org.uk/guidance/ta712> ;
  onco:status "positive" ;
  onco:phase "3" ;
  schema:startDate "2016-03-09" ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mhspc/> ;
  onco:technologies <https://onco.cc/technologies/androgen-deprivation/> ;
  onco:drugs <https://onco.cc/drugs/enzalutamide/> ;
  onco:companies <https://onco.cc/companies/astellas/> ;
  onco:terms <https://onco.cc/terms/prostate-uk-drug-approvals/> ;
  onco:trials <https://onco.cc/trials/enzamet/> ;
  onco:people <https://onco.cc/people/andrew-armstrong/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-arches-j-clin-oncol-2019/>, <https://onco.cc/key-papers/paper-arches-eur-urol-2026-update/> .