# OnCo record arhgef12 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/arhgef12/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "arhgef12" ;
  schema:name "ARHGEF12"@en ;
  schema:alternateName "Rho guanine nucleotide exchange factor 12"@en, "KIAA0382"@en, "ARHGEF12" ;
  schema:description "ARHGEF12 (Rho guanine nucleotide exchange factor 12) is a gene whose normal job is to hold cell growth in check. The public catalogues list it as an oncogene driver, a tumour suppressor and a fusion partner, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Breast cancer, Renal cell carcinoma, Skin cancer and 5 more."@en ;
  schema:url <https://onco.cc/targets/arhgef12/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:14193>, <https://www.uniprot.org/uniprotkb/Q9NZN5/entry>, <https://www.ncbi.nlm.nih.gov/gene/23365>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000196914> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "tumor-suppressor" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:14193>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000196914>, <https://www.uniprot.org/uniprotkb/Q9NZN5/entry>, <https://www.ncbi.nlm.nih.gov/gene/23365> ;
  onco:related <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/clear-cell-rcc/>, <https://onco.cc/cancers/melanoma/> .