# OnCo record arnt (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/arnt/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "arnt" ;
  schema:name "ARNT"@en ;
  schema:alternateName "aryl hydrocarbon receptor nuclear translocator"@en, "Aryl hydrocarbon receptor nuclear translocator"@en, "HIF1B"@en, "HIF-1beta"@en, "bHLHe2"@en, "ARNT1"@en, "ARNT" ;
  schema:description "ARNT (Aryl hydrocarbon receptor nuclear translocator) is a gene whose normal job is to hold cell growth in check. The public catalogues list it as a drug target and a tumour suppressor, and an approved or late-stage drug is recorded against it. Tied to Skin cancer, Breast cancer, Small-cell lung cancer and 1 more."@en ;
  schema:url <https://onco.cc/targets/arnt/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:700>, <https://www.uniprot.org/uniprotkb/P27540/entry>, <https://www.ncbi.nlm.nih.gov/gene/405>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000143437> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "tumor-suppressor" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:700>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000143437>, <https://www.uniprot.org/uniprotkb/P27540/entry>, <https://www.ncbi.nlm.nih.gov/gene/405> ;
  onco:related <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/sclc/>, <https://onco.cc/cancers/melanoma/> ;
  onco:drugs <https://onco.cc/drugs/belzutifan/> ;
  onco:pathways <https://onco.cc/pathways/hif-vhl/> .