# OnCo record ascent-04 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/ascent-04/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "ascent-04", "NCT05382286" ;
  schema:name "ASCENT-04 / KEYNOTE-D19"@en ;
  schema:description "Showed that pairing an ADC with immunotherapy beats chemotherapy plus immunotherapy in first-line PD-L1-positive TNBC."@en ;
  schema:url <https://onco.cc/trials/ascent-04/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT05382286>, <https://doi.org/10.1056/NEJMoa2508959> ;
  onco:status "positive" ;
  onco:phase "3" ;
  schema:startDate "2022-07-25" ;
  onco:cancers <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/tnbc-metastatic/> ;
  onco:technologies <https://onco.cc/technologies/adc/>, <https://onco.cc/technologies/topoisomerase-inhibitors/> ;
  onco:drugs <https://onco.cc/drugs/sacituzumab-govitecan/>, <https://onco.cc/drugs/pembrolizumab/> ;
  onco:companies <https://onco.cc/companies/gilead/>, <https://onco.cc/companies/merck/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-ascent-04-n-engl-j-med-2026/> .