# OnCo record aspen-wm (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/aspen-wm/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "aspen-wm", "NCT03053440" ;
  schema:name "ASPEN (Waldenström macroglobulinaemia)"@en ;
  schema:alternateName "ASPEN"@en, "BGB-3111-302"@en ;
  schema:description "ASPEN compared two BTK inhibitors head to head in Waldenström macroglobulinaemia: zanubrutinib did not produce statistically more deep responses than ibrutinib, but it caused far fewer heart rhythm problems and other side effects, which is why many guidelines now prefer it."@en ;
  schema:url <https://onco.cc/trials/aspen-wm/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03053440> ;
  onco:status "mixed" ;
  onco:tag "subtype-trials" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/waldenstrom/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/> ;
  onco:drugs <https://onco.cc/drugs/zanubrutinib/>, <https://onco.cc/drugs/ibrutinib/> ;
  onco:companies <https://onco.cc/companies/beone/> ;
  onco:people <https://onco.cc/people/constantine-tam/> .