# OnCo record ataxia-telangiectasia (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/ataxia-telangiectasia/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "ataxia-telangiectasia" ;
  schema:name "Ataxia-telangiectasia"@en ;
  schema:alternateName "ataxia telangiectasia"@en, "biallelic ATM"@en ;
  schema:description "Ataxia-telangiectasia is a rare inherited condition, caused by two faulty copies of the ATM gene, that affects balance and movement, the immune system and the lungs, and raises the risk of lymphoma and leukaemia in childhood and of breast and other cancers later. Cancer treatment has to be adapted because people with it are very sensitive to radiotherapy and some chemotherapy."@en ;
  schema:url <https://onco.cc/terms/ataxia-telangiectasia/> ;
  schema:dateModified "2026-11-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Ataxia–telangiectasia> ;
  schema:citation <https://doi.org/10.1158/1078-0432.ccr-24-1098>, <https://doi.org/10.1158/1078-0432.ccr-17-0465>, <https://www.orpha.net/en/disease/detail/100>, <https://www.england.nhs.uk/wp-content/uploads/2018/08/rare-and-inherited-disease-national-genomics-test-directory-v9.xlsx> ;
  onco:tag "gap-fill", "hereditary" ;
  onco:cancers <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:technologies <https://onco.cc/technologies/germline-testing/> ;
  onco:targets <https://onco.cc/targets/atm/> ;
  onco:terms <https://onco.cc/terms/hereditary-cancer-syndromes/> .