# OnCo record atr (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/atr/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "atr" ;
  schema:name "ATR"@en ;
  schema:description "ATR is a DNA-damage alarm kinase. Blocking it makes tumours with broken repair systems collapse under their own replication stress."@en ;
  schema:url <https://onco.cc/targets/atr/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Ataxia_telangiectasia_and_Rad3_related>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:882>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000175054>, <https://www.uniprot.org/uniprotkb/Q13535/entry>, <https://www.ncbi.nlm.nih.gov/gene/545> ;
  owl:sameAs <http://www.wikidata.org/entity/Q4812911> ;
  schema:citation <https://en.wikipedia.org/wiki/Ataxia_telangiectasia_and_Rad3_related> ;
  onco:tag "ddr" ;
  schema:alternateName "ATR" ;
  onco:targetClass "kinase" ;
  onco:firstDescribed "1996"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/tnbc/> ;
  onco:drugs <https://onco.cc/drugs/ceralasertib/> ;
  onco:companies <https://onco.cc/companies/callio-therapeutics/>, <https://onco.cc/companies/repare-therapeutics/> ;
  onco:pathways <https://onco.cc/pathways/ddr/>, <https://onco.cc/pathways/dna-replication-licensing/> .