# OnCo record atrx (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/atrx/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "atrx" ;
  schema:name "ATRX"@en ;
  schema:alternateName "ATRX chromatin remodeler"@en, "Chromatin remodeler ATRX"@en, "XH2"@en, "RAD54"@en, "MRX52"@en, "ATRX" ;
  schema:description "ATRX (Chromatin remodeler ATRX) is a protein that switches other genes on and off. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor, a biomarker and a DNA repair gene, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Sarcomas, Neuroendocrine tumours, Adrenocortical carcinoma and 5 more."@en ;
  schema:url <https://onco.cc/targets/atrx/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:886>, <https://www.uniprot.org/uniprotkb/P46100/entry>, <https://www.ncbi.nlm.nih.gov/gene/546>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000085224> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:886>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000085224>, <https://www.uniprot.org/uniprotkb/P46100/entry>, <https://www.ncbi.nlm.nih.gov/gene/546> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/sarcoma/>, <https://onco.cc/cancers/neuroendocrine/>, <https://onco.cc/cancers/adrenocortical/>, <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/skin-cancer/> ;
  onco:pathways <https://onco.cc/pathways/telomere-maintenance/> .