# OnCo record autogene-cevumeran-phase-1 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/autogene-cevumeran-phase-1/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "autogene-cevumeran-phase-1", "NCT04161755" ;
  schema:name "Autogene cevumeran phase 1 in resected pancreatic cancer (Memorial Sloan Kettering)"@en ;
  schema:alternateName "Rojas 2023"@en, "BNT122 pancreatic phase 1"@en, "RO7198457 pancreatic phase 1"@en ;
  schema:description "This is the small New York trial behind the excitement about personalised mRNA cancer vaccines: half of the 16 patients vaccinated after pancreatic surgery made strong T cells against their own tumour mutations, and those responders had far fewer relapses after more than three years, with vaccine-induced T cells predicted to last for years."@en ;
  schema:url <https://onco.cc/trials/autogene-cevumeran-phase-1/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT04161755>, <https://doi.org/10.1038/s41586-023-06063-y>, <https://doi.org/10.1038/s41586-024-08508-4> ;
  onco:status "active" ;
  onco:phase "1" ;
  onco:cancers <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/resectable-pdac/> ;
  onco:technologies <https://onco.cc/technologies/neoantigen-mrna-vaccine/>, <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:drugs <https://onco.cc/drugs/autogene-cevumeran/>, <https://onco.cc/drugs/atezolizumab/>, <https://onco.cc/drugs/folfirinox/> ;
  onco:companies <https://onco.cc/companies/biontech/>, <https://onco.cc/companies/roche-genentech/> ;
  onco:institutions <https://onco.cc/institutions/mskcc/> ;
  onco:terms <https://onco.cc/terms/cold-vs-hot/>, <https://onco.cc/terms/mrd/> ;
  onco:trials <https://onco.cc/trials/nct05968326/> ;
  onco:people <https://onco.cc/people/vinod-balachandran/> .