# OnCo record axelopran (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/axelopran/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "axelopran" ;
  schema:name "Axelopran"@en ;
  schema:description "Axelopran is a pill that blocks opioid effects outside the brain. Glycyx Therapeutics is testing it with immunotherapy in head and neck cancer in people who take opioids for pain."@en ;
  schema:url <https://onco.cc/drugs/axelopran/> ;
  schema:dateModified "2026-11-04"^^xsd:date ;
  schema:citation <https://www.glycyx.com/our-science>, <https://clinicaltrials.gov/study/NCT07662720> ;
  onco:status "phase-2" ;
  onco:tag "pipeline" ;
  onco:modality "Oral peripherally acting mu-opioid receptor antagonist" ;
  onco:targets <https://onco.cc/targets/oprm1/> ;
  onco:companies <https://onco.cc/companies/glycyx-therapeutics/> ;
  onco:trials <https://onco.cc/trials/nct07354919/> .