# OnCo record b-generic-repurposing (bottleneck). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/bottlenecks/b-generic-repurposing/>
  a schema:Thing ;
  onco:kind "bottleneck" ;
  schema:identifier "b-generic-repurposing" ;
  schema:name "No incentive to repurpose cheap drugs"@en ;
  schema:description "Old, cheap drugs with anti-cancer signals never get the trials they need because no one profits from the result."@en ;
  schema:url <https://onco.cc/bottlenecks/b-generic-repurposing/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.3332/ecancer.2014.442>, <https://doi.org/10.1001/jama.2022.6147>, <https://doi.org/10.1016/S0140-6736(20)30366-4>, <https://www.england.nhs.uk/medicines-2/medicines-repurposing-programme/> ;
  onco:related <https://onco.cc/collections/drugbank-chembl/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/ideas/idea-reg-global-repurposing-fund/>, <https://onco.cc/ideas/idea-reg-third-party-label-update/>, <https://onco.cc/ideas/idea-reg-repurposing-prize/>, <https://onco.cc/ideas/idea-reg-repurposing-social-impact-bond/>, <https://onco.cc/ideas/idea-reg-recovery-style-platform-repurposing/>, <https://onco.cc/ideas/idea-reg-perioperative-propranolol-etodolac/>, <https://onco.cc/ideas/idea-reg-statin-hcc-prevention-trial/>, <https://onco.cc/ideas/idea-reg-evidence-gate-before-repurposing-phase3/>, <https://onco.cc/ideas/idea-reg-target-trial-emulation-pipeline/>, <https://onco.cc/ideas/idea-reg-new-indication-exclusivity-off-patent/>, <https://onco.cc/ideas/idea-reg-delinked-market-entry-reward/>, <https://onco.cc/ideas/idea-reg-generic-targeted-therapy-drup/>, <https://onco.cc/ideas/idea-reg-antihistamine-plus-io-trial/>, <https://onco.cc/ideas/idea-reg-losartan-pancreatic-stroma/>, <https://onco.cc/ideas/idea-reg-regulator-ready-repurposing-dossiers/>, <https://onco.cc/ideas/idea-reg-guideline-fast-track-repurposed/>, <https://onco.cc/ideas/idea-reg-payer-coverage-off-label-generic-commitment/>, <https://onco.cc/ideas/idea-reg-nonprofit-marketing-authorisation-holder/>, <https://onco.cc/ideas/idea-reg-metronomic-lmic-phase3-to-label/>, <https://onco.cc/ideas/idea-reg-generic-chemo-strategic-reserve/>, <https://onco.cc/ideas/idea-reg-factorial-addon-arms-cooperative-trials/>, <https://onco.cc/ideas/idea-reg-preregistered-ai-repurposing-scoring/>, <https://onco.cc/ideas/idea-moon-generics-for-cancer-fund/> ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/neuroblastoma/> ;
  onco:technologies <https://onco.cc/technologies/chemoprevention/>, <https://onco.cc/technologies/ai-drug-design/> ;
  onco:drugs <https://onco.cc/drugs/eflornithine/> ;
  onco:companies <https://onco.cc/companies/us-worldmeds/>, <https://onco.cc/companies/recursion/>, <https://onco.cc/companies/cctg/> ;
  onco:institutions <https://onco.cc/institutions/cruk/>, <https://onco.cc/institutions/nci/> ;
  onco:terms <https://onco.cc/terms/lynch-syndrome/>, <https://onco.cc/terms/real-world-evidence/> ;
  onco:trials <https://onco.cc/trials/nmtrc003/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-pantziarka-ecancermedicalscience/>, <https://onco.cc/key-papers/paper-goodwin-jama/> .