# OnCo record b-translational-valley (bottleneck). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/bottlenecks/b-translational-valley/>
  a schema:Thing ;
  onco:kind "bottleneck" ;
  schema:identifier "b-translational-valley" ;
  schema:name "The valley of death between lab and product"@en ;
  schema:description "Most academic discoveries die before anyone tests them in people because nobody funds the middle step."@en ;
  schema:url <https://onco.cc/bottlenecks/b-translational-valley/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1038/453840a>, <https://doi.org/10.1016/S0002-9343(03)00013-5>, <https://next.cancer.gov/>, <https://ncats.nih.gov/> ;
  onco:related <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/depmap/>, <https://onco.cc/ideas/idea-fund-national-drug-development-office/>, <https://onco.cc/ideas/idea-fund-academic-sponsor-indemnity-pool/>, <https://onco.cc/ideas/idea-moon-public-phase1-factory/> ;
  onco:sections <https://onco.cc/fronts/drug-discovery/> ;
  onco:technologies <https://onco.cc/technologies/ai-drug-design/>, <https://onco.cc/technologies/protac-degrader/>, <https://onco.cc/technologies/crispr-screens/> ;
  onco:companies <https://onco.cc/companies/recursion/>, <https://onco.cc/companies/insilico-medicine/>, <https://onco.cc/companies/isomorphic-labs/>, <https://onco.cc/companies/generate-biomedicines/> ;
  onco:institutions <https://onco.cc/institutions/nci/>, <https://onco.cc/institutions/cruk/>, <https://onco.cc/institutions/broad-institute/>, <https://onco.cc/institutions/francis-crick/>, <https://onco.cc/institutions/dkfz/>, <https://onco.cc/institutions/icr-london/>, <https://onco.cc/institutions/nki/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-butler-nature/>, <https://onco.cc/key-papers/paper-contopoulos-ioannidis-am-j-med/> .