# OnCo record b2m (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/b2m/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "b2m" ;
  schema:name "B2M"@en ;
  schema:alternateName "beta-2-microglobulin"@en, "Beta-2-microglobulin"@en, "B2M" ;
  schema:description "B2M (Beta-2-microglobulin) is a gene whose normal job is to hold cell growth in check. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Non-Hodgkin lymphoma, Colorectal cancer, Lung cancer and 5 more."@en ;
  schema:url <https://onco.cc/targets/b2m/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:914>, <https://www.uniprot.org/uniprotkb/P61769/entry>, <https://www.ncbi.nlm.nih.gov/gene/567>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000166710> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "tumor-suppressor" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:914>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000166710>, <https://www.uniprot.org/uniprotkb/P61769/entry>, <https://www.ncbi.nlm.nih.gov/gene/567> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/non-hodgkin-lymphoma/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/head-and-neck/>, <https://onco.cc/cancers/cervical/>, <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/mantle-cell-lymphoma/> ;
  onco:pathways <https://onco.cc/pathways/antigen-presentation-immunoediting/> .