# OnCo record b7-h3-expression (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/b7-h3-expression/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "b7-h3-expression" ;
  schema:name "B7-H3 (CD276) expression"@en ;
  schema:alternateName "B7-H3"@en, "CD276 expression"@en, "B7-H3 positive"@en ;
  schema:description "B7-H3 is an immune checkpoint protein overexpressed on small-cell lung, prostate and many solid tumours. Ifinatamab deruxtecan is in phase 3 for small-cell lung cancer without an expression cut-off; nothing is approved."@en ;
  schema:url <https://onco.cc/biomarkers/b7-h3-expression/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT06203210> ;
  onco:tag "biomarker", "surface-antigen", "no-threshold" ;
  onco:related <https://onco.cc/biomarkers/dll3-expression/> ;
  onco:cancers <https://onco.cc/cancers/sclc/>, <https://onco.cc/cancers/extensive-stage-sclc/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:drugs <https://onco.cc/drugs/ifinatamab-deruxtecan/> .