# OnCo record bap1-loss (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/bap1-loss/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "bap1-loss" ;
  schema:name "BAP1 loss"@en ;
  schema:alternateName "BAP1"@en, "BAP1 mutation"@en, "BAP1-mutated"@en, "BAP1 immunohistochemistry"@en, "BAP1 nuclear loss"@en, "BAP1-negative"@en, "BAP1 tumour predisposition syndrome"@en, "BAP1-TPDS"@en, "germline BAP1"@en, "BAP1-inactivated melanocytic tumour"@en, "BAP1-deficient"@en ;
  schema:description "BAP1 is a tumour-suppressor gene that mesothelioma, uveal melanoma and clear-cell kidney cancer lose more often than any other; a lost nuclear stain on the biopsy confirms cancer over a benign look-alike in mesothelioma, marks the metastasis-prone half of eye melanomas, and, when inherited, defines a family syndrome of all three."@en ;
  schema:url <https://onco.cc/terms/bap1-loss/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/BAP1> ;
  schema:citation <https://en.wikipedia.org/wiki/BAP1> ;
  onco:related <https://onco.cc/terms/ihc/>, <https://onco.cc/terms/cdkn2a-homozygous-deletion/>, <https://onco.cc/terms/uveal-melanoma-prognostic-markers/>, <https://onco.cc/terms/hereditary-cancer-syndromes/>, <https://onco.cc/technologies/germline-testing/>, <https://onco.cc/drugs/tazemetostat/>, <https://onco.cc/targets/ezh2/> ;
  onco:cancers <https://onco.cc/cancers/pleural-mesothelioma/>, <https://onco.cc/cancers/peritoneal-mesothelioma/>, <https://onco.cc/cancers/uveal-melanoma/>, <https://onco.cc/cancers/clear-cell-rcc/>, <https://onco.cc/cancers/intrahepatic-cholangiocarcinoma/> .