# OnCo record bax (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/bax/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "bax" ;
  schema:name "BAX"@en ;
  schema:alternateName "BCL2L4"@en, "BCL2 associated X, apoptosis regulator"@en, "BAX" ;
  schema:description "BAX is the protein that opens the mitochondria to start cell death. BCL-2 keeps it in check in leukaemia cells; venetoclax and sonrotoclax free it, so the mitochondria leak cytochrome c and the cell dies."@en ;
  schema:url <https://onco.cc/targets/bax/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:959>, <https://www.uniprot.org/uniprotkb/Q07812/entry>, <https://www.ncbi.nlm.nih.gov/gene/581> ;
  onco:tag "wave5-target" ;
  onco:targetClass "other" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:959>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000087088>, <https://www.uniprot.org/uniprotkb/Q07812/entry>, <https://www.ncbi.nlm.nih.gov/gene/581> ;
  onco:related <https://onco.cc/drugs/venetoclax/>, <https://onco.cc/drugs/sonrotoclax/>, <https://onco.cc/targets/bcl2/>, <https://onco.cc/targets/bim/> ;
  onco:cancers <https://onco.cc/cancers/cll/>, <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/dlbcl/> ;
  onco:technologies <https://onco.cc/technologies/bcl2-inhibitors/> ;
  onco:pathways <https://onco.cc/pathways/apoptosis-bcl2/> .