# OnCo record bcg-vaccine-manufacturing (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/bcg-vaccine-manufacturing/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "bcg-vaccine-manufacturing" ;
  schema:name "BCG manufacturing and the bladder cancer BCG shortage"@en ;
  schema:description "BCG, the century-old tuberculosis vaccine, is the best treatment for early bladder cancer, but it is a live bacterium that grows slowly and only one company makes it for the United States. Since 2019 urologists have been splitting doses and rationing courses."@en ;
  schema:url <https://onco.cc/technologies/bcg-vaccine-manufacturing/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://www.accessdata.fda.gov/scripts/drugshortages/>, <https://www.fda.gov/vaccines-blood-biologics/safety-availability-biologics/cber-regulated-products-current-shortages>, <https://www.ashp.org/drug-shortages/current-shortages>, <https://en.wikipedia.org/wiki/BCG_vaccine> ;
  onco:status "standard-of-care" ;
  onco:tag "manufacturing-wave" ;
  onco:cancers <https://onco.cc/cancers/urothelial/> ;
  onco:sections <https://onco.cc/fronts/immunotherapy/> ;
  onco:technologies <https://onco.cc/technologies/pharmaceutical-gmp-inspections/>, <https://onco.cc/technologies/generic-drug-shortage-response/>, <https://onco.cc/technologies/engineered-bacteria-therapy/> ;
  onco:drugs <https://onco.cc/drugs/bcg-intravesical/>, <https://onco.cc/drugs/gemcitabine/>, <https://onco.cc/drugs/docetaxel/> ;
  onco:companies <https://onco.cc/companies/merck/>, <https://onco.cc/companies/sanofi/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-drug-pricing/> .