# OnCo record bcma-then-gprc5d (pairing). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pairings/bcma-then-gprc5d/>
  a schema:MedicalTherapy ;
  onco:kind "pairing" ;
  schema:identifier "bcma-then-gprc5d" ;
  schema:name "BCMA-directed therapy → GPRC5D-directed therapy"@en ;
  schema:description "When a BCMA drug stops working, switching to a drug against a different myeloma protein still produces responses in about two-thirds of patients."@en ;
  schema:url <https://onco.cc/pairings/bcma-then-gprc5d/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT04634552> ;
  onco:cancers <https://onco.cc/cancers/multiple-myeloma/> ;
  onco:targets <https://onco.cc/targets/bcma/>, <https://onco.cc/targets/gprc5d/> ;
  onco:trials <https://onco.cc/trials/monumental-1/> ;
  onco:pairs <https://onco.cc/drugs/teclistamab/>, <https://onco.cc/drugs/talquetamab/> .