# OnCo record bh3-profiling (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/bh3-profiling/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "bh3-profiling" ;
  schema:name "BH3 profiling (functional apoptosis testing)"@en ;
  schema:description "A lab test that measures how close a leukaemia cell is to self-destructing, and which survival protein is holding it back, to predict response to venetoclax-type drugs."@en ;
  schema:url <https://onco.cc/technologies/bh3-profiling/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Bcl-2_family> ;
  owl:sameAs <http://www.wikidata.org/entity/Q554446> ;
  schema:citation <https://en.wikipedia.org/wiki/Bcl-2_family> ;
  onco:status "emerging" ;
  onco:related <https://onco.cc/technologies/bcl2-inhibitors/> ;
  onco:cancers <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/cll/> ;
  onco:sections <https://onco.cc/fronts/diagnostics/>, <https://onco.cc/fronts/drug-discovery/> ;
  onco:technologies <https://onco.cc/technologies/functional-drug-testing/> ;
  onco:targets <https://onco.cc/targets/bcl2/> ;
  onco:drugs <https://onco.cc/drugs/venetoclax/>, <https://onco.cc/drugs/sonrotoclax/> ;
  onco:pathways <https://onco.cc/pathways/apoptosis-bcl2/> ;
  onco:trials <https://onco.cc/trials/nct03223662/> .