# OnCo record birc6 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/birc6/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "birc6" ;
  schema:name "BIRC6"@en ;
  schema:alternateName "baculoviral IAP repeat containing 6"@en, "Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6"@en, "BRUCE"@en, "BIRC6" ;
  schema:description "BIRC6 (Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6) is an enzyme. The public catalogues list it as an oncogene driver, a tumour suppressor and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Bladder & urothelial cancer, Breast cancer, Renal cell carcinoma and 5 more."@en ;
  schema:url <https://onco.cc/targets/birc6/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:13516>, <https://www.uniprot.org/uniprotkb/Q9NR09/entry>, <https://www.ncbi.nlm.nih.gov/gene/57448>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000115760> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "enzyme" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:13516>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000115760>, <https://www.uniprot.org/uniprotkb/Q9NR09/entry>, <https://www.ncbi.nlm.nih.gov/gene/57448> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/urothelial/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/rcc/>, <https://onco.cc/cancers/endometrial/>, <https://onco.cc/cancers/anal/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/hcc/>, <https://onco.cc/cancers/head-and-neck/> .