# OnCo record bonner-cetuximab-rt (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/bonner-cetuximab-rt/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "bonner-cetuximab-rt", "NCT00004227" ;
  schema:name "Bonner trial (cetuximab plus radiotherapy)"@en ;
  schema:description "The Bonner trial was the first to show that a targeted antibody improves survival when added to radiotherapy: cetuximab with radiotherapy lengthened survival in head and neck cancer, and became the option for patients who cannot have cisplatin."@en ;
  schema:url <https://onco.cc/trials/bonner-cetuximab-rt/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT00004227>, <https://doi.org/10.1056/NEJMoa053422> ;
  onco:status "positive" ;
  onco:tag "radiation-wave4" ;
  onco:phase "3" ;
  schema:startDate "1999-04" ;
  onco:cancers <https://onco.cc/cancers/head-and-neck/>, <https://onco.cc/cancers/oropharyngeal-cancer/>, <https://onco.cc/cancers/laryngeal-cancer/>, <https://onco.cc/cancers/hypopharyngeal-cancer/> ;
  onco:technologies <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/radiosensitisers/> ;
  onco:drugs <https://onco.cc/drugs/cetuximab/> .