# OnCo record bpdcn (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/bpdcn/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "bpdcn" ;
  schema:name "Blastic plasmacytoid dendritic cell neoplasm (BPDCN)"@en ;
  schema:description "Blastic plasmacytoid dendritic cell neoplasm is a rare aggressive leukaemia-like blood cancer of dendritic-cell precursors, a few hundred US cases a year, that often first appears as bruise-like skin lesions. Two CD123-directed drugs, tagraxofusp and pivekimab sunirine, are the first targeted therapies; allogeneic transplant in first remission is still the only route to long-term control."@en ;
  schema:url <https://onco.cc/cancers/bpdcn/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Blastic_plasmacytoid_dendritic_cell_neoplasm> ;
  owl:sameAs <http://www.wikidata.org/entity/Q4677939> ;
  schema:citation <https://doi.org/10.1056/NEJMoa1815105> ;
  onco:tag "gap-fill", "haematologic", "rare" ;
  onco:related <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/all-leukemia/> ;
  onco:technologies <https://onco.cc/technologies/adc/>, <https://onco.cc/technologies/allogeneic-hsct/>, <https://onco.cc/technologies/cytokine-therapy/> ;
  onco:targets <https://onco.cc/targets/cd123/>, <https://onco.cc/targets/bcl2/> ;
  onco:drugs <https://onco.cc/drugs/tagraxofusp/>, <https://onco.cc/drugs/pivekimab-sunirine/>, <https://onco.cc/drugs/venetoclax/> ;
  onco:companies <https://onco.cc/companies/abbvie/>, <https://onco.cc/companies/menarini/> ;
  onco:pathways <https://onco.cc/pathways/apoptosis-bcl2/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-pemmaraju-n-engl-j-med/> ;
  onco:pipeline <https://onco.cc/drugs/pivekimab-sunirine/>, <https://onco.cc/drugs/venetoclax/>, <https://onco.cc/technologies/allogeneic-hsct/> ;
  onco:standardOfCare <https://onco.cc/drugs/tagraxofusp/>, <https://onco.cc/drugs/pivekimab-sunirine/>, <https://onco.cc/drugs/venetoclax/>, <https://onco.cc/technologies/allogeneic-hsct/>, <https://onco.cc/technologies/autologous-stem-cell-transplant/>, <https://onco.cc/drugs/venetoclax/>, <https://onco.cc/drugs/pivekimab-sunirine/> .