# OnCo record braf-class-ii-iii (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/braf-class-ii-iii/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "braf-class-ii-iii" ;
  schema:name "BRAF class II and class III mutations (non-V600)"@en ;
  schema:alternateName "BRAF class II"@en, "BRAF class III"@en, "non-V600 BRAF"@en, "BRAF K601E"@en, "BRAF G469A"@en, "BRAF D594G"@en, "atypical BRAF mutation"@en, "BRAF non-V600E"@en ;
  schema:description "Class II and III BRAF mutations sit outside codon 600 and signal as pairs (class II) or by leaning on RAS (class III). Approved BRAF inhibitors do not work on them, and no drug is yet approved for them; pan-RAF inhibitors are in trials."@en ;
  schema:url <https://onco.cc/biomarkers/braf-class-ii-iii/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ea3a9631-3a66-6a7c-e053-2995a90ae2ad> ;
  onco:tag "biomarker", "braf", "no-approval" ;
  onco:related <https://onco.cc/biomarkers/braf-v600e/>, <https://onco.cc/biomarkers/braf-fusion/> ;
  onco:cancers <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/thyroid/> ;
  onco:drugs <https://onco.cc/drugs/tovorafenib/>, <https://onco.cc/drugs/trametinib/> ;
  onco:terms <https://onco.cc/terms/braf-v600-mutation/>, <https://onco.cc/terms/driver-passenger-model/> .