# OnCo record braf-v600-mutation (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/braf-v600-mutation/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "braf-v600-mutation" ;
  schema:name "BRAF V600E mutation"@en ;
  schema:alternateName "V600E"@en, "V600"@en, "BRAF V600E"@en, "BRAF V600"@en, "BRAF-mutant"@en, "BRAF-mutated"@en, "BRAF mutation"@en, "BRAF-mutant melanoma"@en, "BRAF/MEK"@en, "BRAF + MEK"@en, "class II BRAF"@en, "class III BRAF"@en, "BRAF inhibitor"@en, "MEK inhibitor"@en, "BRAF inhibitors"@en, "MEK inhibitors"@en ;
  schema:description "A single spelling change in the BRAF gene that jams a growth switch permanently on. It is found in half of melanomas and in some colon, thyroid, lung and brain tumours, and is treated with a BRAF pill plus a MEK pill."@en ;
  schema:url <https://onco.cc/terms/braf-v600-mutation/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/BRAF_(gene)> ;
  schema:citation <https://en.wikipedia.org/wiki/BRAF_(gene)> ;
  onco:related <https://onco.cc/terms/driver-mutation/>, <https://onco.cc/terms/tumour-agnostic/>, <https://onco.cc/terms/tki-term/> ;
  onco:cancers <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/thyroid/>, <https://onco.cc/cancers/nsclc/> ;
  onco:sections <https://onco.cc/fronts/targeted-therapy/> ;
  onco:targets <https://onco.cc/targets/braf/> ;
  onco:drugs <https://onco.cc/drugs/vemurafenib/> .