# OnCo record brain-metastases (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/brain-metastases/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "brain-metastases" ;
  schema:name "Brain metastases (intracranial disease)"@en ;
  schema:alternateName "brain metastasis"@en, "intracranial"@en, "intracranial metastases"@en, "CNS metastases"@en, "CNS disease"@en, "CNS activity"@en, "intracranial response"@en, "intracranial ORR"@en, "CNS relapse"@en, "brain mets"@en, "intracranial responses"@en ;
  schema:description "Tumour deposits that have travelled to the brain from a cancer elsewhere, ten times more common than cancers that start in the brain, mostly from lung, breast, melanoma and kidney cancer. Because the blood-brain barrier excludes most drugs, whether a medicine reaches and shrinks them now decides which drug is chosen, and trials report intracranial progression separately."@en ;
  schema:url <https://onco.cc/terms/brain-metastases/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Brain_metastasis> ;
  schema:citation <https://en.wikipedia.org/wiki/Brain_metastasis>, <https://doi.org/10.1001/jama.2016.9839>, <https://tnbcfoundation.org/living-with-tnbc/living-with-metastatic-tnbc>, <https://www.cancerresearchuk.org/about-cancer/lung-cancer/metastatic/symptoms>, <https://www.nice.org.uk/guidance/ng122/chapter/Palliative-interventions-and-supportive-and-palliative-care> ;
  onco:related <https://onco.cc/terms/stereotactic-radiosurgery/>, <https://onco.cc/terms/wbrt/>, <https://onco.cc/terms/cns-penetration/>, <https://onco.cc/terms/leptomeningeal-disease/> ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/breast-her2-positive/>, <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/secondary-brain-tumours/>, <https://onco.cc/cancers/lung-cancer/>, <https://onco.cc/cancers/sclc/> ;
  onco:sections <https://onco.cc/fronts/radiation/> .