# OnCo record brca-germline (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/brca-germline/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "brca-germline" ;
  schema:name "Germline BRCA1/2 pathogenic variant (gBRCAm)"@en ;
  schema:alternateName "gBRCA"@en, "gBRCAm"@en, "germline BRCA"@en, "germline BRCA1"@en, "germline BRCA2"@en, "BRCA carrier"@en, "inherited BRCA mutation"@en, "deleterious germline BRCA mutation"@en ;
  schema:description "A germline BRCA1 or BRCA2 variant is inherited and present in every cell, found by a blood test. It selects PARP inhibitors in breast, ovarian, pancreatic and prostate cancer and tells relatives they may carry it too."@en ;
  schema:url <https://onco.cc/biomarkers/brca-germline/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=741ff3e3-dc1a-45a6-84e5-2481b27131aa>, <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=13839d4f-6acf-4ffb-a128-79df59319273> ;
  onco:tag "biomarker", "brca" ;
  onco:related <https://onco.cc/biomarkers/brca-somatic/>, <https://onco.cc/biomarkers/hrd-positive/> ;
  onco:cancers <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/high-grade-serous-ovarian-cancer/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:drugs <https://onco.cc/drugs/olaparib/>, <https://onco.cc/drugs/talazoparib/>, <https://onco.cc/drugs/niraparib/>, <https://onco.cc/drugs/rucaparib/>, <https://onco.cc/drugs/bracanalysis-cdx/> ;
  onco:terms <https://onco.cc/terms/gbrca-mutation/>, <https://onco.cc/terms/germline-vs-somatic/>, <https://onco.cc/terms/hrd/> .