# OnCo record brca-somatic (biomarker). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/biomarkers/brca-somatic/>
  a schema:MedicalTest ;
  onco:kind "biomarker" ;
  schema:identifier "brca-somatic" ;
  schema:name "Tumour (somatic or germline) BRCA1/2 mutation and HRR gene alterations"@en ;
  schema:alternateName "somatic BRCA"@en, "sBRCA"@en, "tumor BRCA"@en, "tBRCA"@en, "BRCAm"@en, "BRCA-mutated"@en, "HRR gene mutation"@en, "HRRm"@en, "homologous recombination repair gene alteration"@en, "ATM mutation"@en, "PALB2 mutation"@en ;
  schema:description "Tumour BRCA testing finds BRCA1/2 mutations in the cancer itself, whether inherited or acquired; wider panels add other repair genes such as ATM and PALB2. Ovarian and prostate cancer labels accept the tumour result for PARP inhibitors."@en ;
  schema:url <https://onco.cc/biomarkers/brca-somatic/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=741ff3e3-dc1a-45a6-84e5-2481b27131aa>, <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0295d202-1cfe-7659-e063-6294a90a476e>, <https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=13839d4f-6acf-4ffb-a128-79df59319273> ;
  onco:tag "biomarker", "brca" ;
  onco:related <https://onco.cc/biomarkers/brca-germline/>, <https://onco.cc/biomarkers/hrd-positive/> ;
  onco:cancers <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/high-grade-serous-ovarian-cancer/>, <https://onco.cc/cancers/platinum-sensitive-ovarian-cancer/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:drugs <https://onco.cc/drugs/olaparib/>, <https://onco.cc/drugs/rucaparib/>, <https://onco.cc/drugs/talazoparib/>, <https://onco.cc/drugs/niraparib/>, <https://onco.cc/drugs/foundationone-cdx/>, <https://onco.cc/drugs/mychoice-cdx/> ;
  onco:terms <https://onco.cc/terms/hrd/>, <https://onco.cc/terms/germline-vs-somatic/>, <https://onco.cc/terms/brca-reversion-mutations/>, <https://onco.cc/terms/ngs/> .