# OnCo record brd4 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/brd4/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "brd4" ;
  schema:name "BRD4"@en ;
  schema:alternateName "BET"@en, "BET bromodomain proteins (BRD2, BRD3, BRD4, BRDT)"@en, "bromodomain containing 4"@en, "MCAP"@en, "HUNK1"@en, "BRD4" ;
  schema:description "BRD4 is a reader protein that docks on acetylated DNA packaging and pulls in the machinery that switches growth genes such as MYC on. BET inhibitors such as pelabresib and ZEN-3694 block that docking; in NUT carcinoma the cancer's own driver is a BRD4 fusion."@en ;
  schema:url <https://onco.cc/targets/brd4/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:13575>, <https://www.uniprot.org/uniprotkb/O60885/entry>, <https://www.ncbi.nlm.nih.gov/gene/23476> ;
  onco:tag "wave5-target" ;
  onco:targetClass "transcription" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:13575>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000141867>, <https://www.uniprot.org/uniprotkb/O60885/entry>, <https://www.ncbi.nlm.nih.gov/gene/23476> ;
  onco:related <https://onco.cc/pathways/myc/>, <https://onco.cc/targets/jak2/> ;
  onco:cancers <https://onco.cc/cancers/nut-carcinoma/>, <https://onco.cc/cancers/primary-myelofibrosis/>, <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/tnbc/> ;
  onco:technologies <https://onco.cc/technologies/epigenetic-drugs/> ;
  onco:drugs <https://onco.cc/drugs/pelabresib/>, <https://onco.cc/drugs/zen-3694/>, <https://onco.cc/drugs/fedratinib/> ;
  onco:pathways <https://onco.cc/pathways/transcription-addiction/>, <https://onco.cc/pathways/epigenetic-reprogramming/>, <https://onco.cc/pathways/myc/> .