# OnCo record brexucabtagene-autoleucel (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/brexucabtagene-autoleucel/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "brexucabtagene-autoleucel" ;
  schema:name "Brexucabtagene autoleucel"@en ;
  schema:description "Brexucabtagene autoleucel is the CAR-T therapy for mantle cell lymphoma and adult acute lymphoblastic leukaemia, giving long remissions after BTK inhibitors fail."@en ;
  schema:url <https://onco.cc/drugs/brexucabtagene-autoleucel/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Brexucabtagene_autoleucel> ;
  owl:sameAs <http://www.wikidata.org/entity/Q97704053> ;
  schema:citation <https://doi.org/10.1056/NEJMoa1914347>, <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=Tecartus> ;
  onco:status "approved" ;
  onco:tag "gap-fill" ;
  onco:modality "Autologous CD19 CAR-T (CD28 costimulatory domain)" ;
  schema:alternateName "Tecartus" ;
  onco:approval "US 2020: Relapsed/refractory mantle cell lymphoma", "US 2021: Relapsed/refractory B-ALL in adults", "EU 2020: MCL after ≥2 lines including a BTK inhibitor" ;
  onco:acceleratedApproval "US 2020-07-24: Treatment of adult patients with relapsed or refractory mantle cell lymphoma (MCL)." ;
  onco:acceleratedApprovalConfirmed "US 2026-04-01: Treatment of adult patients with relapsed or refractory mantle cell lymphoma (MCL)." ;
  onco:cancers <https://onco.cc/cancers/mantle-cell-lymphoma/>, <https://onco.cc/cancers/all-leukemia/> ;
  onco:technologies <https://onco.cc/technologies/car-t/> ;
  onco:targets <https://onco.cc/targets/cd19/> ;
  onco:companies <https://onco.cc/companies/gilead/> ;
  onco:terms <https://onco.cc/terms/crs/>, <https://onco.cc/terms/icans/> ;
  onco:trials <https://onco.cc/trials/nct06253663/> .