# OnCo record brf113928 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/brf113928/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "brf113928", "NCT01336634" ;
  schema:name "BRF113928 cohort C (dabrafenib with trametinib, untreated BRAF V600E)"@en ;
  schema:alternateName "BRF113928"@en ;
  schema:description "Thirty-six patients showed that the melanoma combination of a BRAF and a MEK drug also works in the small slice of lung cancers with the same mutation."@en ;
  schema:url <https://onco.cc/trials/brf113928/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT01336634>, <https://doi.org/10.1016/S1470-2045(17)30679-4>, <https://www.nice.org.uk/guidance/ta898> ;
  onco:status "positive" ;
  onco:phase "2" ;
  onco:cancers <https://onco.cc/cancers/braf-v600e-nsclc/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/> ;
  onco:targets <https://onco.cc/targets/braf/> ;
  onco:drugs <https://onco.cc/drugs/dabrafenib/>, <https://onco.cc/drugs/trametinib/>, <https://onco.cc/drugs/dabrafenib-trametinib/> ;
  onco:companies <https://onco.cc/companies/novartis/> ;
  onco:pathways <https://onco.cc/pathways/ras-mapk/> ;
  onco:terms <https://onco.cc/terms/braf-v600-mutation/>, <https://onco.cc/terms/driver-mutation/> ;
  onco:trials <https://onco.cc/trials/pharos/> .