# OnCo record btla (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/btla/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "btla" ;
  schema:name "BTLA"@en ;
  schema:alternateName "B and T lymphocyte associated"@en, "CD272"@en, "BTLA1"@en, "BTLA" ;
  schema:description "BTLA is a brake on T and B cells that is pressed by HVEM, a molecule many tumours carry. An antibody that blocks it is being tested with PD-1 blockade in small-cell lung cancer."@en ;
  schema:url <https://onco.cc/targets/btla/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:21087>, <https://www.uniprot.org/uniprotkb/Q7Z6A9/entry>, <https://www.ncbi.nlm.nih.gov/gene/151888>, <https://clinicaltrials.gov/study/NCT06095583> ;
  onco:tag "checkpoint-map" ;
  onco:targetClass "checkpoint" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:21087>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000186265>, <https://www.uniprot.org/uniprotkb/Q7Z6A9/entry>, <https://www.ncbi.nlm.nih.gov/gene/151888> ;
  onco:related <https://onco.cc/targets/tnfrsf14/>, <https://onco.cc/drugs/toripalimab/>, <https://onco.cc/targets/pd1/> ;
  onco:cancers <https://onco.cc/cancers/sclc/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:pathways <https://onco.cc/pathways/pd1-checkpoint/> .