# OnCo record busulfan (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/busulfan/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "busulfan" ;
  schema:name "Busulfan"@en ;
  schema:alternateName "Busilvex"@en, "Myleran / Busulfex" ;
  schema:description "Busulfan is one of the oldest cancer drugs. As a tablet it controlled chronic myeloid leukaemia before imatinib; as an infusion it is used to clear the bone marrow before a stem cell transplant."@en ;
  schema:url <https://onco.cc/drugs/busulfan/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Busulfan> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=busulfan>, <https://www.cancer.gov/about-cancer/treatment/drugs/busulfan>, <https://www.ema.europa.eu/en/medicines/human/EPAR/busilvex> ;
  onco:status "approved" ;
  onco:tag "nci-list" ;
  onco:modality "Alkylating agent (alkyl sulfonate)" ;
  onco:approval "US 1954: Palliative treatment of chronic myelogenous leukaemia (Myleran tablets)", "US 1999: Conditioning with cyclophosphamide before allogeneic HPC transplantation for CML (Busulfex)", "EU 2003: Conditioning before haematopoietic progenitor cell transplantation (Busilvex)" ;
  onco:cancers <https://onco.cc/cancers/cml/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/allogeneic-hsct/> ;
  onco:companies <https://onco.cc/companies/otsuka/> .