# OnCo record cadonilimab (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/cadonilimab/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "cadonilimab" ;
  schema:name "Cadonilimab"@en ;
  schema:description "A Chinese two-armed antibody that blocks PD-1 and CTLA-4 together, approved in China for cervical cancer and extending survival even in PD-L1-negative tumours."@en ;
  schema:url <https://onco.cc/drugs/cadonilimab/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Cadonilimab> ;
  onco:status "approved" ;
  onco:modality "Bispecific antibody (PD-1×CTLA-4)" ;
  schema:alternateName "Kaitanni" ;
  onco:approval "China 2022: Recurrent/metastatic cervical cancer after platinum", "China 2024: First-line persistent/recurrent/metastatic cervical cancer with chemotherapy ± bevacizumab; first-line gastric cancer with chemotherapy" ;
  onco:cancers <https://onco.cc/cancers/cervical/>, <https://onco.cc/cancers/gastric/> ;
  onco:technologies <https://onco.cc/technologies/bispecific-antibody/>, <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:targets <https://onco.cc/targets/pd1/>, <https://onco.cc/targets/ctla4/> ;
  onco:companies <https://onco.cc/companies/akeso/> ;
  onco:pathways <https://onco.cc/pathways/pd1-checkpoint/> ;
  onco:trials <https://onco.cc/trials/compassion-16/>, <https://onco.cc/trials/nct05489289/>, <https://onco.cc/trials/nct07412613/>, <https://onco.cc/trials/nct06617416/>, <https://onco.cc/trials/nct06371157/>, <https://onco.cc/trials/nct05932212/>, <https://onco.cc/trials/nct06646055/>, <https://onco.cc/trials/nct05904379/>, <https://onco.cc/trials/nct07052253/>, <https://onco.cc/trials/nct07245446/>, <https://onco.cc/trials/nct06560112/>, <https://onco.cc/trials/nct06530251/>, <https://onco.cc/trials/nct05235516/>, <https://onco.cc/trials/nct05944224/>, <https://onco.cc/trials/nct06221748/>, <https://onco.cc/trials/nct07023315/>, <https://onco.cc/trials/nct05859750/> .