# OnCo record cancer-metabolism (pathway). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pathways/cancer-metabolism/>
  a schema:BioChemEntity ;
  onco:kind "pathway" ;
  schema:identifier "cancer-metabolism" ;
  schema:name "Cancer metabolism"@en ;
  schema:description "Cancer cells rewire how they eat. They burn glucose inefficiently but fast (the Warburg effect), gorge on glutamine and fats, and build the nucleotides and lipids needed to divide. This is why the FDG PET scan works, and why metabolism is a drug target."@en ;
  schema:url <https://onco.cc/pathways/cancer-metabolism/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Warburg_effect_(oncology)> ;
  owl:sameAs <http://www.wikidata.org/entity/Q2904886> ;
  schema:citation <https://doi.org/10.1016/j.cmet.2022.01.007> ;
  onco:tag "mechanism" ;
  onco:technologies <https://onco.cc/technologies/fdg-pet/>, <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:targets <https://onco.cc/targets/idh/>, <https://onco.cc/targets/pik3ca/>, <https://onco.cc/targets/hif2a/> ;
  onco:drugs <https://onco.cc/drugs/ivosidenib/>, <https://onco.cc/drugs/vorasidenib/> ;
  onco:institutions <https://onco.cc/institutions/mskcc/>, <https://onco.cc/institutions/md-anderson/>, <https://onco.cc/institutions/penn-abramson/>, <https://onco.cc/institutions/francis-crick/> ;
  onco:pathways <https://onco.cc/pathways/pi3k-akt-mtor/>, <https://onco.cc/pathways/myc/>, <https://onco.cc/pathways/hif-vhl/> ;
  onco:terms <https://onco.cc/terms/warburg-effect/>, <https://onco.cc/terms/deregulating-cellular-energetics/>, <https://onco.cc/terms/suv/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-pavlova-cell-metab-2022/> .