# OnCo record car-t-lymphodepletion (protocol). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/protocols/car-t-lymphodepletion/>
  a schema:MedicalGuideline ;
  onco:kind "protocol" ;
  schema:identifier "car-t-lymphodepletion" ;
  schema:name "Lymphodepleting chemotherapy before CAR T-cell infusion"@en ;
  schema:alternateName "lymphodepletion"@en, "LD chemotherapy"@en, "Flu/Cy"@en, "fludarabine and cyclophosphamide conditioning"@en, "lymphodepleting conditioning"@en ;
  schema:description "A few days before CAR T cells are given, a short course of chemotherapy, usually fludarabine and cyclophosphamide, lowers your own white cells to make room for the CAR T cells to grow. The team first checks that your CAR T cells are ready and that you have no uncontrolled infection. The doses and timing follow the instructions for your product."@en ;
  schema:url <https://onco.cc/protocols/car-t-lymphodepletion/> ;
  schema:dateModified "2026-11-11"^^xsd:date ;
  onco:tag "protocol", "cell-therapy", "car-t" ;
  onco:related <https://onco.cc/protocols/car-t-bridging/>, <https://onco.cc/protocols/car-t-infection-prevention/>, <https://onco.cc/protocols/icaht-prolonged-cytopenia/> ;
  onco:cancers <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/follicular-lymphoma/>, <https://onco.cc/cancers/all-leukemia/> ;
  onco:technologies <https://onco.cc/technologies/car-t/> ;
  onco:drugs <https://onco.cc/drugs/fludarabine/>, <https://onco.cc/drugs/cyclophosphamide/>, <https://onco.cc/drugs/bendamustine/>, <https://onco.cc/drugs/axicabtagene-ciloleucel/>, <https://onco.cc/drugs/tisagenlecleucel/> ;
  onco:terms <https://onco.cc/terms/lymphodepletion/>, <https://onco.cc/terms/lymphoma-tx-car-t-pathway/> .