# OnCo record casp8 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/casp8/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "casp8" ;
  schema:name "CASP8"@en ;
  schema:alternateName "caspase 8"@en, "Caspase-8"@en, "MCH5"@en, "FLICE"@en, "Casp-8"@en, "CASP8" ;
  schema:description "CASP8 (Caspase-8) is an enzyme. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Head and neck squamous cell carcinoma, Skin cancer, Cervical cancer and 5 more."@en ;
  schema:url <https://onco.cc/targets/casp8/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1509>, <https://www.uniprot.org/uniprotkb/Q14790/entry>, <https://www.ncbi.nlm.nih.gov/gene/841>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000064012> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "enzyme" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1509>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000064012>, <https://www.uniprot.org/uniprotkb/Q14790/entry>, <https://www.ncbi.nlm.nih.gov/gene/841> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/head-and-neck/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/cervical/>, <https://onco.cc/cancers/breast-cancer/>, <https://onco.cc/cancers/nasopharyngeal/>, <https://onco.cc/cancers/urothelial/>, <https://onco.cc/cancers/non-hodgkin-lymphoma/>, <https://onco.cc/cancers/gastric/> .