# OnCo record castration-resistance (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/castration-resistance/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "castration-resistance" ;
  schema:name "Castration-resistant prostate cancer (CRPC)"@en ;
  schema:alternateName "hormone-relapsed prostate cancer"@en, "hormone-relapsed"@en, "hormone relapsed"@en, "hormone-refractory prostate cancer"@en ;
  schema:description "Prostate cancer that keeps growing even though testosterone has been reduced to castrate levels."@en ;
  schema:url <https://onco.cc/terms/castration-resistance/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Castration-resistant_prostate_cancer> ;
  schema:citation <https://en.wikipedia.org/wiki/Castration-resistant_prostate_cancer>, <https://www.nice.org.uk/guidance/ng131/chapter/Recommendations> ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:pathways <https://onco.cc/pathways/ar-signaling/> ;
  onco:terms <https://onco.cc/terms/ar-v7/>, <https://onco.cc/terms/tnm-prostate-cancer/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-visakorpi-androgen-receptor-amplification-nat-genet-1995/>, <https://onco.cc/key-papers/paper-chen-androgen-receptor-overexpression-antiandrogen-resistance-nat-med-2004/>, <https://onco.cc/key-papers/paper-quigley-structural-variation-mcrpc-cell-2018/>, <https://onco.cc/key-papers/paper-abida-genomic-correlates-outcome-mcrpc-pnas-2019/> .