# OnCo record caution-pd1-first-line-ovarian (pairing). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pairings/caution-pd1-first-line-ovarian/>
  a schema:MedicalTherapy ;
  onco:kind "pairing" ;
  schema:identifier "caution-pd1-first-line-ovarian" ;
  schema:name "Caution: checkpoint inhibitors in first-line ovarian cancer"@en ;
  schema:description "Immunotherapy added to first-line chemotherapy has failed to extend survival in ovarian cancer in every large trial so far; its only win is in PD-L1-positive platinum-resistant disease."@en ;
  schema:url <https://onco.cc/pairings/caution-pd1-first-line-ovarian/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT03737643>, <https://clinicaltrials.gov/study/NCT05116189> ;
  onco:cancers <https://onco.cc/cancers/ovarian/> ;
  onco:targets <https://onco.cc/targets/pd1/>, <https://onco.cc/targets/pdl1/> ;
  onco:trials <https://onco.cc/trials/duo-o/>, <https://onco.cc/trials/keynote-b96/> ;
  onco:pairs <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/cancers/ovarian/> .