# OnCo record cbl (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/cbl/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "cbl" ;
  schema:name "CBL"@en ;
  schema:alternateName "Cbl proto-oncogene"@en, "E3 ubiquitin-protein ligase CBL"@en, "RNF55"@en, "c-Cbl"@en, "CBL2"@en, "CBL" ;
  schema:description "CBL (E3 ubiquitin-protein ligase CBL) is an enzyme. The public catalogues list it as a drug target, an oncogene driver, a tumour suppressor and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Myeloproliferative neoplasms, Leukaemia, Skin cancer and 5 more."@en ;
  schema:url <https://onco.cc/targets/cbl/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1541>, <https://www.uniprot.org/uniprotkb/P22681/entry>, <https://www.ncbi.nlm.nih.gov/gene/867>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000110395> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "enzyme" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1541>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000110395>, <https://www.uniprot.org/uniprotkb/P22681/entry>, <https://www.ncbi.nlm.nih.gov/gene/867> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/>, <https://onco.cc/collections/intogen/> ;
  onco:cancers <https://onco.cc/cancers/myeloproliferative-neoplasms/>, <https://onco.cc/cancers/leukaemia/>, <https://onco.cc/cancers/skin-cancer/>, <https://onco.cc/cancers/esophageal/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/sarcoma/>, <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/nsclc/> ;
  onco:pathways <https://onco.cc/pathways/rtk-activation/> .