# OnCo record cd137 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/cd137/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "cd137" ;
  schema:name "CD137 (4-1BB, TNFRSF9)"@en ;
  schema:alternateName "4-1BB"@en, "CD137"@en, "ILA"@en, "TNF receptor superfamily member 9"@en, "TNFRSF9" ;
  schema:description "4-1BB is a switch on activated T cells that makes them live longer and kill better. Rather than press it everywhere, new bispecific antibodies press it only on T cells that are already touching a tumour cell marked by PD-L1 or HER2."@en ;
  schema:url <https://onco.cc/targets/cd137/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11924>, <https://www.uniprot.org/uniprotkb/Q07011/entry>, <https://www.ncbi.nlm.nih.gov/gene/3604> ;
  onco:tag "wave5-target" ;
  onco:targetClass "surface-antigen" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11924>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000049249>, <https://www.uniprot.org/uniprotkb/Q07011/entry>, <https://www.ncbi.nlm.nih.gov/gene/3604> ;
  onco:related <https://onco.cc/targets/pdl1/>, <https://onco.cc/targets/her2/>, <https://onco.cc/targets/cd28/> ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/gastric/> ;
  onco:technologies <https://onco.cc/technologies/bispecific-antibody/> ;
  onco:drugs <https://onco.cc/drugs/acasunlimab/>, <https://onco.cc/drugs/cinrebafusp-alfa/> ;
  onco:pathways <https://onco.cc/pathways/cancer-immunity-cycle/>, <https://onco.cc/pathways/pd1-checkpoint/> .