# OnCo record cd27 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/cd27/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "cd27" ;
  schema:name "CD27"@en ;
  schema:alternateName "TNFRSF7"@en, "CD27 molecule"@en, "Tp55"@en, "S152"@en, "CD27" ;
  schema:description "CD27 is an accelerator on most T cells that is pressed by CD70. Agonist antibodies against it reached phase 2 in lymphoma; its partner CD70 is a separate target for antibodies and CAR-T cells."@en ;
  schema:url <https://onco.cc/targets/cd27/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11922>, <https://www.uniprot.org/uniprotkb/P26842/entry>, <https://www.ncbi.nlm.nih.gov/gene/939>, <https://clinicaltrials.gov/study/NCT03038672> ;
  onco:tag "checkpoint-map" ;
  onco:targetClass "surface-antigen" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11922>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000139193>, <https://www.uniprot.org/uniprotkb/P26842/entry>, <https://www.ncbi.nlm.nih.gov/gene/939> ;
  onco:related <https://onco.cc/targets/cd70/>, <https://onco.cc/drugs/nivolumab/>, <https://onco.cc/targets/cd137/> ;
  onco:cancers <https://onco.cc/cancers/dlbcl/> ;
  onco:pathways <https://onco.cc/pathways/cancer-immunity-cycle/> .