# OnCo record cd3 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/cd3/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "cd3" ;
  schema:name "CD3"@en ;
  schema:description "CD3 is the switch on every T cell. Bispecific drugs grab it with one arm and the tumour with the other, forcing the T cell to attack."@en ;
  schema:url <https://onco.cc/targets/cd3/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/CD3_(immunology)>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1674>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000198851>, <https://www.uniprot.org/uniprotkb/P07766/entry>, <https://www.ncbi.nlm.nih.gov/gene/916> ;
  owl:sameAs <http://www.wikidata.org/entity/Q419458> ;
  schema:citation <https://en.wikipedia.org/wiki/CD3_(immunology)>, <https://doi.org/10.1038/nrc2542> ;
  onco:tag "t-cell-engager-target" ;
  schema:alternateName "CD3E" ;
  onco:targetClass "surface-antigen" ;
  onco:firstDescribed "1986"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/non-hodgkin-lymphoma/> ;
  onco:drugs <https://onco.cc/drugs/catumaxomab/>, <https://onco.cc/drugs/asp2138/>, <https://onco.cc/drugs/azd0486/>, <https://onco.cc/drugs/tqb2825/>, <https://onco.cc/drugs/azd6621/>, <https://onco.cc/drugs/cart84/>, <https://onco.cc/drugs/azd5863/> ;
  onco:companies <https://onco.cc/companies/asher-bio/>, <https://onco.cc/companies/cullinan-therapeutics/>, <https://onco.cc/companies/cytomx-therapeutics/>, <https://onco.cc/companies/harpoon-therapeutics/>, <https://onco.cc/companies/janux-therapeutics/> .