# OnCo record cd40 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/cd40/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "cd40" ;
  schema:name "CD40"@en ;
  schema:alternateName "TNFRSF5"@en, "CD40 molecule"@en, "Bp50"@en, "p50"@en, "CD40" ;
  schema:description "CD40 sits on the cells that teach T cells what to attack. Agonist antibodies press it to turn cold tumours hot; the strongest signals so far are in pancreatic cancer with chemotherapy."@en ;
  schema:url <https://onco.cc/targets/cd40/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11919>, <https://www.uniprot.org/uniprotkb/P25942/entry>, <https://www.ncbi.nlm.nih.gov/gene/958>, <https://europepmc.org/article/MED/31412220> ;
  onco:tag "checkpoint-map" ;
  onco:targetClass "surface-antigen" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11919>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000101017>, <https://www.uniprot.org/uniprotkb/P25942/entry>, <https://www.ncbi.nlm.nih.gov/gene/958> ;
  onco:related <https://onco.cc/targets/cd28/>, <https://onco.cc/terms/macrophage/> ;
  onco:cancers <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/melanoma/> ;
  onco:technologies <https://onco.cc/technologies/cd40-agonists/> ;
  onco:drugs <https://onco.cc/drugs/selicrelumab/>, <https://onco.cc/drugs/mitazalimab/> ;
  onco:pathways <https://onco.cc/pathways/cancer-immunity-cycle/> .