# OnCo record cdc7 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/cdc7/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "cdc7" ;
  schema:name "CDC7"@en ;
  schema:alternateName "cell division cycle 7"@en, "CDC7 kinase"@en, "DDK"@en, "CDC7" ;
  schema:description "CDC7 is the kinase that switches on the starting points of DNA copying in each cell cycle. Cancer cells starved of it attempt to copy their DNA anyway and die, while normal cells pause; a CDC7 inhibitor is in trials for acute myeloid leukaemia and myelodysplastic syndromes."@en ;
  schema:url <https://onco.cc/targets/cdc7/> ;
  schema:dateModified "2026-11-03"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1745>, <https://www.uniprot.org/uniprotkb/O00311/entry>, <https://www.ncbi.nlm.nih.gov/gene/8317>, <https://doi.org/10.1158/0008-5472.CAN-04-1547> ;
  onco:tag "pipeline-gap-target" ;
  onco:targetClass "kinase" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1745>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000097046>, <https://www.uniprot.org/uniprotkb/O00311/entry>, <https://www.ncbi.nlm.nih.gov/gene/8317> ;
  onco:cancers <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/mds/> ;
  onco:drugs <https://onco.cc/drugs/sgr-2921/> .