# OnCo record cdk11 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/cdk11/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "cdk11" ;
  schema:name "CDK11"@en ;
  schema:alternateName "cyclin dependent kinase 11"@en, "CDK11A"@en, "CDK11B"@en, "PITSLRE"@en ;
  schema:description "CDK11 is an enzyme that helps the cell's splicing machinery cut and join its gene messages correctly. Blocking it leaves messages unfinished; one CDK11 inhibitor is in preclinical development."@en ;
  schema:url <https://onco.cc/targets/cdk11/> ;
  schema:dateModified "2026-11-03"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1730>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:1729>, <https://www.uniprot.org/uniprotkb/P21127/entry>, <https://doi.org/10.1038/s41586-022-05204-z> ;
  onco:tag "pipeline-gap-target" ;
  onco:targetClass "kinase" ;
  onco:cancers <https://onco.cc/cancers/metastatic-cancer/> ;
  onco:drugs <https://onco.cc/drugs/acr-6840/> .
